4685 Centennial Blvd, Colorado Springs, CO 80919
+1 800-331-2303



BioComp is a specialized laboratory dedicated to investigating the reactivity potential of restorative materials, especially in the field of dentistry.

The immune system is the body’s natural defense against pathogens, whether bacterial, viral, fungal, or parasitic. However, the immune system also defends the body against antigens, which are molecules that do not contain the body’s own HCC (i.e., histocompatibility complex) on its surface, and are therefore recognized as “non-self.” Therefore, they are capable of inducing an immune response in the host organism. Sometimes, antigens even can attach themselves to the host, and the body inaccurately recognizes “the whole complex” as antigenic – something to be gotten rid of. When the immune system detects either an invading pathogen or an antigen (i.e., anything that is not identifiable as either part of the body or compatible with it), it reacts with an immune response. This is designed to quarantine and/or destroy the detected threat.

Reactivity is the amount of change that occurs in the immune system upon exposure to a foreign substance.

An allergy is a reaction on the part of the body to an allergen: a foreign substance that elicits an immune response.

Biocompatibility is the degree to which a given substance does not elicit an immune response from a particular individual.

Dental toxicity is the complex condition resulting from both the cumulative effects derived from the placement of biologically incompatible materials in the mouth and their potential to do harm.

Restorative materials replace the function and appearance of a natural tooth. However, no restorative material can fully replace its biological original, especially at a vital or energetic level.

The kinds of materials available for use in dental restorations are incredibly varied. Dentists use everything from metals to ceramics to plastics or composites, and even cadaver parts.

The metallic materials commonly used in conventional dentistry are mercury amalgams and casting alloys.

The metallic materials commonly used in conventional dentistry are mercury amalgams and casting alloys.

Dental composites are usually a particular combination of resin, silica, and quartz. For this reason, these composites are generally safer and more generally biocompatible alternative to dental amalgams.

Most people would be surprised to know that older dentures used a mercuric compound to achieve the pink-gum-look of a denture. Many contemporary dentures still contain bismuth and zinc. The more expensive, more natural-looking denture teeth are sometimes high in aluminum. And you wonder why Grandma can’t remember where she left her teeth, or sometimes even the names of her grandchildren!

There are literally hundreds of different brands of composite materials available for dentists to choose from. Over 50% of them are very high in aluminum. The same holds true for ceramic materials commonly used in conventional dentistry.

Dental toxicity can be avoided, firstly, by keeping mercury, nickel, titanium and all other heavy metals out of your mouth and, secondly, by never allowing someone to talk you into getting a root canal.

BioComp classifies tested materials according to three levels of reactivity with regard to each individual person: least reactive, moderately reactive, and highly reactive.

There is no non-reactive classification, for the simple reason that anything that is not self will elicit at least a small immune reaction.

No, BioComp does not diagnose disease. Rather, it assists healthcare providers in determining which restorative materials are the best options for use with their individual patients.

If the patient’s body is still dealing with foods that have been eaten within the last 12 hours, and some of those foods are allergens, then the reactivity panel will be skewed.

Because we are closed on weekends and even if you overnight your sample, it may sit outdoors in the elements until Monday morning. 

The BioComp test does not use whole blood, but only the serum portion. We must have enough serum to fill a large number of small test tubes.

Test results are usually completed within one week.

Biocomp Labs is dedicated to the investigation of dental material reactivity.